Karen's musical portrait takes the young Georgia from her childhood to her first shocking moments asked to paint nude men at the Academy of Art in Chicago, to New York and back to Chicago, through years of agony and lack of faith in her own talent until the famous photographer Alfred Stieglitz happens to see her work and gives her the recognition she deserves. Stieglitz and Georgia become lifetime partners, although Georgia's passion for the Southwest takes her away from New York. She settles in Abiquiu after Stieglitz' death ; the second act devotes itself to Georgia's years in New Mexico, her wry amusement at the fans who visit her there, her growing blindness and her spiritual journey, drawn in the tones of the eternal river, a philosophical river of her life.